NSC 38240
2-Oxazolidone
CAS: 497-25-6
Molecular Formula: C3H5NO2
NSC 38240 - Names and Identifiers
| Name | 2-Oxazolidone |
| Synonyms | NSC 35382 NSC 38240 2-Oxazolinone 2-Oxazolidone 2-Oxo-1,3-oxazolidine 2-Oxotetrahydro-1,3-oxazole |
| CAS | 497-25-6 |
| EINECS | 207-840-9 |
| InChI | InChI=1/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5) |
NSC 38240 - Physico-chemical Properties
| Molecular Formula | C3H5NO2 |
| Molar Mass | 87.08 |
| Density | 1.204g/cm3 |
| Melting Point | 86-89℃ |
| Boling Point | 324°C at 760 mmHg |
| Flash Point | 165.8°C |
| Vapor Presure | 0.000252mmHg at 25°C |
| Appearance | White-like to yellow-brown crystals |
| Storage Condition | Room Temprature |
| Refractive Index | 1.436 |
| MDL | MFCD00005268 |
| Physical and Chemical Properties | Chemical properties Melting point 86-89 ℃, boiling point 220 ℃(6.38kPa). |
| Use | Used as an organic intermediate |
NSC 38240 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
NSC 38240 - Upstream Downstream Industry
NSC 38240 - Nature
| storage conditions | Sealed in dry,Room Temperature |
| acidity coefficient (pKa) | 12.78±0.20(Predicted) |
| morphology | Crystals or Powder |
| color | Off-white to yellow-beige |
| water solubility | Soluble in water. |
| BRN | 106251 |
| NIST chemical information | Oxazolidin-2-one(497-25-6) |
| EPA chemical information | 2-Oxazolidinone (497-25-6) |
Last Update：2024-04-10 22:29:15
NSC 38240 - Security information
| WGK Germany | 3 |
| RTECS number | RQ2450000 |
| TSCA | Yes |
| customs code | 29322980 |
| Toxicity | TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59 |
Last Update：2024-04-10 22:29:15
NSC 38240 - Uses and synthesis methods
application
2-oxazolidinone can be used in the field of medicine and chemical industry, and 2-oxazolidinone compounds can be used as intermediates for the synthesis of drug molecules, such as as the preparation of pipertine hydrochloride and berberine as intermediate raw materials.
2-oxazolidinone can also be used in the synthesis of daily chemical products such as fibers, reactive dyes, cosmetics, lubricant additives, rust inhibitors and dye auxiliaries. It is also an important intermediate for the synthesis of carbazoptera and cyclohexanitrourea. It can also be used to absorb SO2 from exhaust gas and recycle it through regeneration.
Preparation
The synthesis methods of 2-oxazolidinone mainly include the following: 1) The electrolytic cyclization and oxidation reaction of hydroxyethylformamide; 2) The reaction of aminoethanol and CO2 gas; 3) The reaction of epoxide and cyanuric acid or urea; 4) The reaction of acrolein and isocyanate; 5) The reaction of aziridine and CO2 gas; 7) Reaction of aminoethanol with urea, etc.
use
Intermediates of the drug Carbazopanidon and Cyclohexiride.
Used as an organic intermediate
production method
It is obtained by cyclizing ethanolamine and urea. Urea, ethanolamine and dimethylformamide are added into the reaction pot, stirred and heated to 120 ℃, kept warm for 2 hours, then heated to 150-160 ℃ for reflux for 6 hours, cooled and decompressed to evaporate dimethylformamide, and anhydrous ethanol is added to precipitate crystallization. Filtration, alcohol washing and drying to obtain 2-oxazolidinone with a yield of about 70%.
Last Update：2024-04-09 22:09:11
Supplier List
Featured ProductsSpot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Featured Products
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Oxazolidin-2-one Request for quotationCAS: 497-25-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Oxazolidin-2-one Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Featured Products
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-Oxazolidone Request for quotationCAS: 497-25-6
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Oxazolidin-2-one Request for quotationCAS: 497-25-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Oxazolidin-2-one Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 2-Oxazolidone Visit Supplier Webpage Request for quotationCAS: 497-25-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
Raw Materials for NSC 38240
Downstream Products for NSC 38240
Furazolidone
Lomustine
3-AMINO-2-OXAZOLIDINONE
N,N'-bis-(2-Chloroethyl)urea
2-Chloroethyl isocyanate
3,4-METHYLENEDIOXYPHENETHYLAMINE HYDROCHLORIDE
Lomustine
3-AMINO-2-OXAZOLIDINONE
N,N'-bis-(2-Chloroethyl)urea
2-Chloroethyl isocyanate
3,4-METHYLENEDIOXYPHENETHYLAMINE HYDROCHLORIDE